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    HomeTechHow a 'pan-coronavirus' Army vaccine could beat COVID and all new variants

    How a ‘pan-coronavirus’ Army vaccine could beat COVID and all new variants

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    The Military’s COVID vaccine has demonstrated success in primates, mice and hamsters.


    Marcy Sanchez/US Military

    For probably the most up-to-date information and details about the coronavirus pandemic, go to the WHO and CDC web sites.

    Skyrocketing COVID-19 instances because of the extremely contagious omicron variant have many specialists speaking about yearly boosters or variant-specific vaccines. However what if there have been an adaptable, common coronavirus vaccine that might struggle any COVID variant and even any future coronavirus? That is precisely what the US Military is creating proper now.

    White Home Chief Medical Adviser Dr. Anthony Fauci just lately touted the significance of a common vaccine to guard towards all COVID variants. In an interview with NBC Thursday, Fauci stated a common COVID vaccine “would imply that the preliminary vaccination would cowl all of those little variants, so that you would not have to fret.”

    “We wish a pan-coronavirus vaccine so that you’ve got it on the shelf to reply to the subsequent viral pandemic,” Fauci stated. “Finally, you wish to get a vaccine that covers the whole lot.”

    In December, the US Army announced that its pan-coronavirus vaccine, the spike ferritin nanoparticle COVID-19 vaccine (aka SpFN) had accomplished Section 1 of human trials with constructive outcomes. Dr. Kayvon Modjarrad, director of infectious ailments at Walter Reed Military Institute of Analysis (WRAIR) and co-inventor of SpFN, informed Defense One, “We’re testing our vaccine towards all of the totally different variants, together with omicron,” the pressure causing breakthrough infections even in individuals who have acquired booster photographs. 

    SpFN nonetheless must endure Section 2 and three human trials, although, to check its efficacy and security compared to present therapies, Modjarrad stated. 

    We’ll share what we all know in regards to the Military’s COVID-19 vaccine, together with the way it works and when it may change into out there.

    For extra, study free at-home COVID tests, why you should not “just get COVID over with,”  mixing and matching booster shots, and the difference between N95, KN95, and KF94 masks

    What’s the US Military COVID-19 vaccine?

    The three vaccines approved proper now to be used within the US take two approaches to stopping COVID-19 an infection: The Pfizer and Moderna vaccines use mRNA to construct up immunity, whereas the Johnson & Johnson vaccine makes use of a innocent rhinovirus to coach the physique’s immune system to reply to COVID.

    The Spike Ferritin Nanoparticle COVID-19 vaccine, or SpFN, takes a 3rd strategy, utilizing a innocent portion of the COVID-19 virus to spur the physique’s defenses towards COVID.

    SpFN additionally has much less restrictive storage and dealing with necessities than the Moderna and Pfizer vaccines, permitting it for use in a greater variety of conditions. It may be saved between 36 and 46 levels Fahrenheit for as much as six months and at room temperature for as much as one month, according to military scientists. Pfizer’s vaccine requires an ultracold freezer (between minus 112 and minus 76 levels F) for cargo and storage and is simply stable for 31 days when saved in a fridge.

    The Military’s vaccine has been examined with two photographs, 28 days aside, and likewise with a 3rd shot after six months.

    Will the Military vaccine work towards totally different strains of COVID-19 like omicron and different coronaviruses?

    SpFN is being examined in people towards the omicron variant, in response to Modjarrad, and has proven constructive outcomes.

    The vaccines from Moderna, Pfizer and Johnson & Johnson all goal the precise virus — SARS-CoV-2 — that causes COVID-19. However Military scientists designed their vaccine to be “pan-coronavirus,” which means it may shield towards future strains of COVID in addition to different coronaviruses.

    The Military’s SpFN vaccine is formed like a soccer ball with 24 faces. Scientists can connect the spikes of a number of coronavirus strains to every of the totally different faces, permitting them to customise the vaccine for any new COVID variants that come up.

    “The accelerating emergence of human coronaviruses all through the previous twenty years and the rise of SARS-CoV-2 variants, together with most just lately omicron, underscore the continued want for next-generation preemptive vaccines that confer broad safety towards coronavirus ailments,” Modjarrad said in a statement final month. “Our technique has been to develop a ‘pan-coronavirus’ vaccine expertise that might doubtlessly provide secure, efficient and sturdy safety towards a number of coronavirus strains and species.”


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    When will the Army’s COVID vaccine be available?

    No date has been set. SpFN successfully completed animal testing and wrapped Phase 1 of human trials in December, but it must still complete Phases 2 and 3 of human testing, when its safety and efficacy is compared to current vaccine options. 

    Normally, completing all three phases can take up to five years, but the urgency of the COVID-19 pandemic is speeding up the process. The Moderna, Pfizer and Johnson & Johnson vaccines, for example, were tested, reviewed and authorized by the Food and Drug Administration over the course of one year. 

    What happens next with the Army SpFN vaccine?

    After data from the Phase 1 human trials is collected, analyzed and published, Phase 2 and 3 trials will begin. There is very little information so far on when or how those trials will proceed or if the phases will overlap.

    To follow the progress of the Army vaccine trials, visit the SpFN COVID-19 Vaccine Tracker provided by the US Army Medical Research and Development Command.

    For more on COVID-19, here’s what we know about how the CDC defines being fully vaccinated, how to store your vaccine card on your phone, and what we still don’t know about the virus after two years.

    The information contained in this article is for educational and informational purposes only and is not intended as health or medical advice. Always consult a physician or other qualified health provider regarding any questions you may have about a medical condition or health objectives.

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