Some medication are considered extra highly effective collectively: aspirin and coffee, cannabis and alcohol, and the antibiotics ampicillin and gentamicin, to call a number of. Within the case of most cancers medication, scientists have lengthy thought discovering synergistic medication, the place one agent paves the best way for one more to focus on a tumor extra aggressively, is the epitome of mixture remedy.
However a rising line of analysis is starting to shatter the concept that “synergy” needs to be a excessive precedence in most cancers remedy. The newest research, revealed Thursday in Clinical Cancer Research, examined 13 mixtures with most cancers immunotherapy medication and located that the advantages of all of the pairings appear to come back from every drug independently, not how they work collectively. The discovering factors to a concession in most cancers analysis: For all of the advances made in most cancers biology and mixture remedy, scientists are nonetheless largely at midnight about tumors and the medication that concentrate on them.